Ritchie Edhouse threw Luke Littler of the Championship 12 players at the dramatic end.
The Englishman defeated his 18-year-old compatriots 6-5 in a tense conclusion about a decisive leg in Mattioli Arena in Leicester to book a quarterfinal clearance with Dutchman Gian van Veen.
Little intervened twice the five to try 120 to leave the world no.
The teenager had previously recovered from a 4-1 deficit to lead 5-4, but could not close the match.
In the last eight, Edhouse has joined Josh Rock in Northern Ireland, defeating Danny Noppert 6-3 after hit the nine-track in his third round of victory over Matt Campbel, and will face the next Gary Anderson.
Elsean, Ian White goes to his head with Luke Woodhouse and Jonny Clayton plays Gerwyn Price.
Where does the next Premier League go?
Premier League Darts in Manchester
The Premier League continues on Thursday, April 10, in the AO arena in Manchester as a popular home Littler and a price clash in the Titanical meeting, while Michael van Gerwen is facing Chris Dobey.
Watch Night 10 Premier League Darts in Manchester, Live on Sky Sports Action from 19:00 – stream with now.
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